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Upcoming events

Wednesday, 31 May

Group Meeting - Wes Kramer
05:00 PM to 06:00 PM, May 31, 2017

Chemistry 212 - Spring 2014

Bioinorganic Chemistry
Instructors: TA:
  Theo Agapie   Sandy Suseno
  Jay Winkler  

Organizational Information

Class Times: Mondays & Wednesdays, 10:30 - 11:55 AM, 121 Beckman Institute (note room change)

Lecture Topics (number of lectures):
  • Biogeochemical cycles (1)
  • Structure (1 lecture)
  • Electron transfer in proteins: Photosynthesis and Respiration (3)
  • O2 catalysis (oxygenases, oxidases) (3)
  • Metal Ion Storage & Transport (1)
  • Hydrolysis (1)
  • Electron transfer in DNA (J. K. Barton) (1)
  • Hydrogen, carbon, sulfur, nitrogen metabolism (3)
  • Metals in medicine (1)
  • Nitrogenase (D. C. Rees) (1)
  • Signaling and regulation (2)
  • Radical Enzymes (1)

Suggested References:
Bioinorganic Chemistry, Bertini, Gray, Stiefel, Valentine, Eds, University Science Books, 2007 Principles of Bioinorganic Chemistry, Lippard and Berg, University Science Books, 1994
SPECIAL ISSUE: Dioxygen Activation by Metalloenzymes and Models, Accts. Chem. Res., 2007, 40(7) Long-Range Electron Transfer Special Feature, Proceedings of the National Academy of Sciences, USA, 2005, 102(10)  
Bioinorganic Chemistry Special Feature, Proceedings of the National Academy of Sciences, USA, 2003, 100(7) Bioinorganic Enzymology II, Chemical Reviews, 2014 ASAP
Electron Transfers in Chemistry and Biology, R. A. Marcus and N. Sutin, Biochim. Biophys. Acta 1985, 811, 265-322  


Molecular Viewing Programs:

Requirements and Grading:
  • Literature discussions on recent papers in bioinorganic chemistry (Primary/Secondary Reviews: 10%, In-class participation: 20%)
  • Original research proposal in bioinorganic chemistry (10 pages, 40 %)
  • Team project on a problem related to bioinorganic chemistry (oral presentation by team members, 30 %)

Target Dates:
  • April 14: Proposal Topic Due
  • April 30: First Draft of Research Proposal Due
  • May 14: Research Proposal Due
  • May 12: Project Selection Due
  • May 28: Project Outline Due
  • June 6: Project presentations